Protein-Protein Interactions

Front Matter....Pages I-VII
Introduction....Pages 1-2
Molecular Forces....Pages 3-16
Structure, Function and Dynamics of a Regulatory Enzyme — Aspartate Transcarbamylase....Pages 17-56
Subunits to Superstructures: Assembly of Glutamate Dehydrogenase....Pages 57-90
Subunit Interactions in Haemoglobin....Pages 91-110
Interaction between Chymotrypsin (Trypsin) and the Pancreatic Trypsin Inhibitor (Kallikrein Inactivator)....Pages 111-128
An Example of “Quasi-Irreversible” Protein-Protein Interaction: The Trypsin-Pancreatic Trypsin Inhibitor Complex....Pages 129-138
Subunit Interactions in Lactate Dehydrogenase....Pages 139-158
Cooperative Association....Pages 159-181
Analysis of the Structure of Complex Proteins by Electron Microscopy....Pages 183-211
Probe Studies on the Role of Protein-Protein Interactions and Enzyme Conformation in Control....Pages 213-243
Enzyme-Enzyme Interactions in Tryptophan Synthetase from E. coli....Pages 245-269
Heterologous Enzyme-Enzyme Interactions....Pages 271-297
Influences of Heterologous Protein Interactions on the Control of Glycogen Phosphorylase....Pages 299-315
Protein Assemblies in Muscle....Pages 317-342
The Pyruvate Dehydrogenase Complex of E. coli K-12 Structure and Synthesis....Pages 343-364
The Multienzyme Systems of Fatty Acid Biosynthesis....Pages 365-394
Conformational Changes in Protein Antigens Induced by Specific Antibodies: Sperm-whale Myoglobin....Pages 395-408
Stabilization of Conformations of E. coli ß-Galactosidase by Specific Antibodies. Restrictions in Antigenic Determinants and Antibodies....Pages 409-428
TMV Protein Association and its Role in the Self-Assembly of the Virus....Pages 429-443
Surface Membrane Alterations and Relevance to Cell-Cell Interaction and Growth Control in Tissue Culture....Pages 445-461
Concluding Remarks....Pages 463-464