Peptides as Probes in Muscle Research

Front Matter....Pages I-X
Introduction....Pages 1-5
Structure of Actin....Pages 7-14
Interaction of Actin 1–28 with Myosin and Troponin I and the Importance of These Interactions to Muscle Regulation....Pages 15-31
Probing Myosin Head Structure with Monoclonal Antibodies and Recombinant Technology....Pages 33-37
An Actin-Binding Site on Myosin....Pages 39-48
Competitive Inhibition of Maximum Ca-Activated Force in Skinned Muscle Fibers by Cationic Peptides from the SH-1 Region of Myosin Heavy Chain....Pages 49-55
The Use of Peptide Mimetics to Define the Actin-Binding Sites on the Head of the Myosin Molecule....Pages 57-68
Interference of Myosin Peptides with Weak and Strong Actin Interaction of Cross-Bridges in Skeletal Muscle Fibres....Pages 69-80
Caldesmon Derived Polypeptides as Probes of Force Production in Skeletal Muscle....Pages 81-93
Myosin and Troponin Peptides Affect Calcium Sensitivity of Skinned Muscle Fibres....Pages 95-109
Peptides as Probes of the Mechanisms Regulating Smooth Muscle Contractility: Studies on Skinned Fibres....Pages 111-117
Antibodies as Probes of the Mechanisms Regulating Smooth Muscle Contractility: Studies on Skinned Fibres....Pages 119-129
Regulation of Ca 2+ Release from Sarcoplasmic Reticulum of Skeletal Muscle by an Endogenous Substance....Pages 131-140
Defining Sites and Mechanisms of Interaction Between Rhodopsin and Transducin....Pages 141-149
Comparative Studies on Chicken Skeletal and Smooth Muscle Dystrophins....Pages 151-159
Use of Synthetic Peptides in the Study of the function of Dystrophin....Pages 161-170
Back Matter....Pages 171-174