Autoimmunity: Experimental Aspects

Front Matter....Pages I-XVI
Tolerance induction in mature peripheral T cells....Pages 1-9
Transgenic mice carrying the rearranged T cell receptor of a diabetogenic T cell clone....Pages 11-28
The maintenance and reestablishment of self-tolerance: T cell receptor (TCR) peptide-specific regulatory T cells....Pages 29-37
Prevention of gastric autoimmunity by transgenic expression of a proton pump subunit in the thymus....Pages 39-44
The Anti-Self B Cell Repertoire....Pages 45-50
In vivo suppression of IgG2a b production accomplished by CD4 + 8 − Th1 cell clones specific for a γ2a b allopeptide determinant....Pages 51-57
Expression cloning using antibodies from a patient with rheumatoid arthritis of an autoantigen homologous to the Drosophila splicing regulator, suppressor-of-white-apricot ....Pages 59-73
Use of synthetic peptides for the analysis of B-cell epitopes in autoantigens....Pages 75-90
Molecular mimicry as a mechanism of induction of autoantibodies....Pages 91-97
The Expression of Heat Shock Proteins in Systemic Lupus Erythematosus....Pages 99-129
The heavy chain variable region genes of human lupus autoantibodies....Pages 131-149
Molecular analysis of anti-dsDNA autoantibodies from patients with systemic lupus erythematosus....Pages 151-161
Differential usage of an autoantibody-associated V H gene by human B-cell tumors....Pages 163-172
Idiotypes of DNA-Binding Autoantibodies:Mapping by Epitope Scanning and Molecular Modelling....Pages 173-189
T cell receptor variable gene repertoire in rheumatoid synovial T cells responding to BCG....Pages 191-196
An Analysis of T cell receptor diversity in the NOD mouse: What can it tell us about the autoimmune process?....Pages 197-212
Possible Linkage of Myasthenia Gravis Susceptibility in R111 S/J Mice to a Genomic Deletion of T Cell Receptor Vβ Genes....Pages 213-220
Genetic and environmental factors in Systemic lupus erythematosus....Pages 221-227
Role of Immunocompetent Cells in Skin Sclerosis and Autoimmunity in Tight Skin Mice....Pages 229-243
MRL/ lpr mice as a model of autoimmune diseases: mutiple strategies for immune intervention....Pages 245-258
Major histocompatibility binding peptides: an experimental approach towards specific immunotherapy of autoimmune diseases....Pages 259-273
Type-I (insulin-dependent) and type-II (non-insulin-dependent) diabetes mellitus in BC1[(NODx Mus spretus )F1xNOD] mice....Pages 275-297
Back Matter....Pages 299-308